Thomas A. D'Amico, MD



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Professor of Surgery
Chief, Section of General Thoracic Surgery, Vice Chair of Surgery, Chief Medical Officer of Duke Cancer Institute
Department / Division:
Surgery / Cardiovascular & Thoracic
DUMC 3496
Duke South Rooms 3589
Durham, NC 27710
Appointment Telephone:
Office Telephone:
  • MD, Columbia University College of Physicians and Surgeons (New York), 1987
  • Thoracic Surgery, Duke University Medical Center, 1987-1996
  • Thoracic Oncology, Memorial Sloan-Kettering Cancer Center, 1996
Clinical Interests:
Lung and esophageal cancer; general thoracic and thorocoscopic surgery; minimally invasive thoracic surgery; thoracic oncology; lung volume reduction; photodynamic therapy (PDT); laser bronchoscopy; bronchial and esophageal stents; molecular biology of lung and esophageal cancer
Research Interests:
Lung Cancer

1.Role of molecular markers in the prognosis and therapy of lung cancer
2.Genomic analysis lung cancer mutations

Esophageal Cancer

1.Role of molecular markers in the prognosis and therapy of esophageal cancer
2.Genomic analysis esophageal cancer mutations
Representative Publications:
  • Joshi, MB; D'Amico, TA; Harpole, DH. Molecular biologic substaging of stage I NSCLC through immunohistochemistry performed on formalin-fixed, paraffin-embedded tissue. Methods in Molecular Medicine. 2003;75:369-388.  Abstract
  • D'Amico, TA. Molecular biologic substaging of non-small cell lung cancer. Journal of Thoracic and Cardiovascular Surgery. 2002;123:409-410.  Abstract
  • D'Amico, TA; Wong, TZ; Harpole, DH; Brown, SD; Coleman, RE. Impact of computed tomography-positron emission tomography fusion in staging patients with thoracic malignancies. The Annals of Thoracic Surgery. 2002;74:160-163.  Abstract
  • Daniels, LJ; Balderson, SS; Onaitis, MW; D'Amico, TA. Thoracoscopic lobectomy: a safe and effective strategy for patients with stage I lung cancer. The Annals of Thoracic Surgery. 2002;74:860-864.  Abstract
  • Lau, CL; Moore, MB; Brooks, KR; D'Amico, TA; Harpole, DH. Molecular staging of lung and esophageal cancer. Surgical Clinics of North America. 2002;82:497-523.  Abstract
  • Aloia, TA; Harpole, DH; Reed, CE; Allegra, C; Moore, MB; Herndon, JE; D'Amico, TA. Tumor marker expression is predictive of survival in patients with esophageal cancer. The Annals of Thoracic Surgery. 2001;72:859-866.  Abstract
  • D'Amico, TA; Aloia, TA; Moore, MB; Conlon, DH; Herndon, JE; Kinch, MS; Harpole, DH. Predicting the sites of metastases from lung cancer using molecular biologic markers. The Annals of Thoracic Surgery. 2001;72:1144-1148.  Abstract
  • Harpole, DH; Moore, MB; Herndon, JE; Aloia, T; D'Amico, TA; Sporn, T; Parr, A; Linoila, I; Allegra, C. The prognostic value of molecular marker analysis in patients treated with trimodality therapy for esophageal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. 2001;7:562-569.  Abstract
  • Markert, ML; Alvarez-McLeod, AP; Sempowski, GD; Hale, LP; Horvatinovich, JM; Weinhold, KJ; Bartlett, JA; D'Amico, TA; Haynes, BF. Thymopoiesis in HIV-infected adults after highly active antiretroviral therapy. AIDS Research and Human Retroviruses. 2001;17:1635-1643.  Abstract
  • D'Amico, TA; Aloia, TA; Moore, MB; Herndon, JE; Brooks, KR; Lau, CL; Harpole, DH. Molecular biologic substaging of stage I lung cancer according to gender and histology. The Annals of Thoracic Surgery. 2000;69:882-886.  Abstract
  • D'Amico, TA; Harpole, DH. Molecular biology of esophageal cancer. Chest surgery clinics of North America. 2000;10:451-469.  Abstract
  • Lau, CL; Palmer, SM; Posther, KE; Howell, DN; Reinsmoen, NL; Massey, HT; Tapson, VF; Jaggers, JJ; D'Amico, TA; Davis, RD. Influence of panel-reactive antibodies on posttransplant outcomes in lung transplant recipients. The Annals of Thoracic Surgery. 2000;69:1520-1524.  Abstract
  • Morse, MA; Bossen, E; D'Amico, TA; Williamson, W; Johnson, R. Myxoid liposarcoma of the supraclavicular fossa. Chest. 2000;117:1518-1520.  Abstract
  • Shah, AS; Forbess, JM; Skaryak, LA; Lilly, RE; Vaslef, SN; D'Amico, TA. Emergent thoracotomy for airway control after intrathoracic tracheal injury. Journal of Trauma - Injury, Infection and Critical Care. 2000;48:1163-1164.  Abstract
  • D'Amico, TA; Massey, M; Herndon, JE; Moore, MB; Harpole, DH. A biologic risk model for stage I lung cancer: immunohistochemical analysis of 408 patients with the use of ten molecular markers. Journal of Thoracic and Cardiovascular Surgery. 1999;117:736-743.  Abstract